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Recommended Reading from Tech Founders

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Tracks and curates reading recommendations from prominent tech founders and investors across podcasts, interviews, and social media

Tim Ferriss shares two ketogenesis papers on antibiotic sensitivity and pathogen disruption
Feb 3
2 min read
127 docs
Tim Ferriss
Two research papers Tim Ferriss highlighted as “interesting references” around fasting-induced ketogenesis: one focused on sensitizing bacteria to antibiotics (which he frames as potentially relevant to Lyme treatment), and another showing β-hydroxybutyrate disrupting pathogen development in a malaria model.

Most compelling recommendation: fasting-induced ketogenesis as a lever for antibiotic sensitivity

Fasting-induced ketogenesis sensitizes bacteria to antibiotic treatment

  • Content type: Research paper (PubMed listing)
  • Author/creator: Not specified in the shared post
  • Link/URL (as shared): https://pubmed.ncbi.nlm.nih.gov/40315854/
  • Recommended by: Tim Ferriss
  • Key takeaway (as shared): Ferriss summarizes that fasting-induced ketogenesis can alter host metabolism in ways that increase antibiotic sensitivity in bacteria and modulate immune and inflammatory responses; he adds that, in principle, these effects could enhance standard Lyme disease treatment by strengthening antibiotic efficacy and improving host immune function . He also notes that Borrelia burgdorferi is “an obligate glycolytic (e.g. no TCA/ETC),” which he argues makes the rationale for Lyme management stronger .
  • Why it matters: This is a concrete, mechanism-oriented paper recommendation that Ferriss explicitly frames as relevant to improving how standard antibiotic treatment might work in Lyme disease contexts (via host metabolism and immune/inflammatory modulation) .

A second, adjacent mechanism: ketosis disrupting pathogen development (malaria model)

β-hydroxybutyrate inhibits Plasmodium falciparum development and confers protection against malaria in mice

  • Content type: Research paper (PMC full text)
  • Author/creator: Not specified in the shared post
  • Link/URL (as shared): https://pmc.ncbi.nlm.nih.gov/articles/PMC12286851/
  • Recommended by: Tim Ferriss
  • Key takeaway (as shared): Ferriss notes that while the study is not about Lyme disease, it demonstrates that ketosis can disrupt pathogen development and modulate host immune/inflammatory pathways, creating an environment less favorable for the pathogen while enhancing host immune and mitochondrial resilience .
  • Why it matters: It’s a clearly scoped “mechanism reference” Ferriss uses to support the broader idea that ketosis can shift host-pathogen dynamics through immune/inflammatory and resilience pathways (even though the specific pathogen differs) .
No updates
Feb 2 106 docs
Housing constraints, education pipelines, and a renewed push to rethink the operating system
Feb 1
3 min read
165 docs
Vinod Khosla
scott belsky
ℏεsam
+4
Today’s high-signal picks cluster around structural levers: a research paper on how housing constraints suppress growth, two education-focused reads (standards in Mississippi; China’s “genius” talent pipeline), and a multi-leader signal that OS reimagination is overdue via an OpenClaw/Clawdbot architecture breakdown.

Most compelling recommendation: a research-backed case that housing constraints suppress growth

Hsieh & Moretti paper on housing constraints and US economic growth (growth.pdf)

  • Content type: Research paper
  • Author/creator: Hsieh & Moretti
  • Link/URL (as shared): https://eml.berkeley.edu/~moretti/growth.pdf
  • Recommended by: Garry Tan
  • Key takeaway (as shared): Tan argues the paper shows that blocking housing lets incumbent homeowners “privatize the gains of the American economy” and enforces a “geographic caste system” that locks talent out of opportunity . He also cites claims that housing bans in SF and NYC “strangled 36% of all US economic growth for decades,” costing “$8,775” per American worker each year .
  • Why it matters: If you’re tracking policy bottlenecks that affect labor mobility and opportunity, this is a direct pointer to a single, canonical paper that investors and operators are using to frame the macro cost of local housing restrictions.

Education standards, talent pipelines, and what “support” looks like

“There Really Was a Mississippi Miracle in Reading. States Should Learn From It”

  • Content type: Article
  • Author/creator: Not specified in the shared post
  • Link/URL (as shared): https://www.the74million.org/article/there-really-was-a-mississippi-miracle-in-reading-states-should-learn-from-it/?utm_source=perplexity
  • Recommended by: Garry Tan
  • Key takeaway (as shared): Tan frames the story as evidence that there are real benefits to holding real standards rather than “rubber stamping” grades upward . He summarizes the principle as “High expectations plus real support equals real results” and argues that lowering standards “to be kind” ultimately betrays vulnerable students .
  • Why it matters: It’s a concrete, outcomes-oriented recommendation in an area where debates often stay abstract—Tan is pointing readers to a specific example and a clear operating rule (standards + support) .

“China’s Genius Plan” (FT Magazine feature)

  • Content type: Article / magazine feature
  • Author/creator: @zijing_wu
  • Link/URL (as shared): https://as.ft.com/r/c8abb097-a2c5-4b7a-953e-f46a99ec5076
  • Recommended by: Bill Gurley
  • Key takeaway (as shared): Gurley highlights a program in China where 100K teenagers are funneled each year into a special “genius” track, contrasting it with US school districts canceling “gifted” programs .
  • Why it matters: For readers trying to understand how countries build durable technical advantage, this is flagged as a detailed look at an education pipeline explicitly connected (by the recommender) to AI talent development .

Foundational software: another strong signal that “OS reimagination” is trending among builders

Breakdown of the architecture behind OpenClaw/Clawdbot (X article / thread)

  • Content type: X article / thread
  • Author/creator: @hesamation (as shared)
  • Link/URL (as shared): http://x.com/i/article/2016908271227953152
  • Recommended by: Scott Belsky; also boosted by Vinod Khosla
  • Key takeaway (as shared): Belsky calls it a “good breakdown” of the OpenClaw/Clawdbot architecture and says it makes clear that operating systems are “overdue for reimagination,” adding that “the big OS companies need to lean in hard…this is the future” . Khosla adds: “Worth understanding…” .
  • Why it matters: This is a multi-leader recommendation converging on the same meta-point: emerging architectures like OpenClaw/Clawdbot are being treated as evidence that the OS layer is due for a redesign .

Video: a “worth a watch” interview (shared in a liberalism critique thread)

Interview video (YouTube link)

  • Content type: Video interview
  • Author/creator: Not specified in the shared post
  • Link/URL (as shared): https://youtu.be/pGiNrIxxpe8?si=HlIMDc3riQHFcful
  • Recommended by: Garry Tan
  • Key takeaway (as shared): Tan says the “Original interview is worth a watch” in a thread highlighting arguments about whether “formally equal rules” that produce unequal outcomes are unjust, whether groups (vs individuals) should be the unit of moral concern, and whether past injustice creates present moral debt regardless of individual guilt .
  • Why it matters: If you’re tracking what ideas are shaping current debates among tech leaders, this is a direct pointer to a primary-source interview that Tan explicitly endorses watching .
An OpenClaw/Clawdbot architecture breakdown—and a call to reimagine operating systems
Jan 31
1 min read
181 docs
scott belsky
ℏεsam
One high-signal resource pick: Scott Belsky shares an X article breaking down the architecture behind OpenClaw/Clawdbot, framing it as evidence that operating systems are overdue for reimagination—and urging major OS companies to “lean in hard.”

Most compelling recommendation: an architecture breakdown that argues for rethinking the OS

Breakdown of the architecture behind OpenClaw/Clawdbot

  • Content type: X article
  • Author/creator: Not specified in the shared post (shared via @hesamation)
  • Link/URL (as shared): http://x.com/i/article/2016908271227953152
  • Recommended by: Scott Belsky
  • Key takeaway (as shared): Belsky calls it a “good breakdown” of OpenClaw/Clawdbot’s architecture and says it “makes it perfectly clear that our operating systems are overdue for reimagination,” adding that “the big OS companies need to lean in hard here…this is the future.”
  • Why it matters: This is a clear, high-conviction pointer from Belsky toward OS-level change prompted by emerging architectures like OpenClaw/Clawdbot—useful if you’re tracking where foundational shifts in computing may be headed.

“good breakdown of the architecture behind OpenClaw/Clawdbot, and also makes it perfectly clear that our operating systems are overdue for reimagination.

the big OS companies need to lean in hard here…this is the future”

Shared via:https://x.com/hesamation/status/2017038553058857413

Garry Tan’s recommendations: excellence-focused education principles and a Gokul Rajaram AI/product podcast
Jan 30
2 min read
215 docs
Garry Tan
Gokul Rajaram
Two organic recommendations from Garry Tan: a Substack argument for excellence-focused education (with specific principles like ability grouping, explicit instruction, and accountability), plus a podcast conversation with Gokul Rajaram on AI’s impact on product development and company durability.

Most compelling recommendation: a case for “excellence” in education (with concrete operating principles)

No One Wants to Talk About Excellence

  • Content type: Article (Substack)
  • Author/creator: Center for Educational Progress
  • Link/URL (as shared): https://open.substack.com/pub/educationprogress/p/no-one-wants-to-talk-about-excellence?utm_campaign=post-expanded-share&utm_medium=web
  • Recommended by: Garry Tan (Y Combinator President & CEO)
  • Key takeaway (as shared): Tan highlights the Center for Educational Progress’ goals, including:
    • “Meet students where they are”: ability grouping, acceleration for advanced learners, remediation for those who need it
    • “Embrace the science of learning”: explicit instruction in foundational skills, systematic phonics for reading, practiced fluency for math; defer discovery-based approaches until basics are mastered
    • “Measure what matters”: regular assessment to inform instruction, honest reporting of results, accountability for outcomes; resist lowering standards “in the name of closing gaps”
  • Why it matters: This is a clear, principles-driven recommendation—Tan frames the Center itself as “what we need,” and the excerpted goals make the piece useful as a concrete checklist of instructional and accountability priorities .

“The Center for Educational Progress is what we need.”


Also recommended: a founder/operator podcast conversation on AI-era product building and durability

Gokul Rajaram on Invest Like the Best (with Patrick O’Shaughnessy)

  • Content type: Podcast episode
  • Author/creator: Invest Like the Best (Patrick O’Shaughnessy); guest: Gokul Rajaram
  • Link/URL (as shared): https://x.com/gokulr/status/2016897077293568266
  • Recommended by: Garry Tan
  • Key takeaway (as described): The episode discussion topics include:
    • How AI has transformed product development
    • Durability in the age of AI
    • Which companies will thrive vs. be challenged
    • Lessons from building multiple large ads businesses
  • Why it matters: The topic list is tightly scoped to product strategy and company resilience under AI-driven change—useful if you want an operator-oriented pass across what shifts, what endures, and what business lessons generalize .

“Gokul is a real one. Worth a listen 🎧”

Bill Gurley’s top China reads (Dan Wang, Patrick McGee) and a must-watch AI competition breakdown
Jan 29
2 min read
165 docs
Bill Gurley
Today’s resource picks are anchored by Bill Gurley’s high-conviction recommendations on understanding modern China (two books) plus one “must watch” AI-competition video thread.

Most compelling recommendation: a modern, systems-level read on China

Breakneck

  • Content type: Book
  • Author/creator: Dan Wang
  • Link/URL (as shared): https://a.co/d/e7hQ0Uh
  • Recommended by: Bill Gurley (Benchmark)
  • Key takeaway (per Gurley): Gurley calls it a “must read,” describing it as an “eye-opening very modern look at China”—including “what works & doesn’t,” and “how that reflects on the US.”
  • Why it matters: If you’re trying to update your mental model of modern China (and what that implies for the US), this is presented as a high-conviction, perspective-shaping pick.

Another high-signal China read: supply chain co-evolution through Apple

Apple in China

  • Content type: Book
  • Author/creator: Patrick McGee
  • Link/URL (as shared): https://a.co/d/5jUEhW9
  • Recommended by: Bill Gurley (Benchmark)
  • Key takeaway (per Gurley): A “deep-dive into Apple’s co-evolution with China over the past 20 years,” leaving readers with “a much fuller understanding” of why “modern China is quite different from many’s perception.”
  • Why it matters: A concrete lens (Apple’s 20-year arc) for understanding how modern China developed in ways that can diverge from common narratives.

AI competition (video)

AI “vectors of competition” breakdown (X video post)

  • Content type: Video / X post
  • Author/creator: Dee Bosa (@dee_bosa)
  • Link/URL: https://x.com/dee_bosa/status/2016565482392826059
  • Recommended by: Bill Gurley (Benchmark)
  • Key takeaway (per Gurley): Gurley says “No one is going deeper on AI and all the vectors of competition than @dee_bosa,” and labels it a “Must watch!”
  • Why it matters: A strong, unambiguous endorsement that this is unusually thorough on AI competition dynamics.
A high-conviction sales/marketing podcast, maker-vs-manager scheduling, and two Balaji reads
Jan 28
2 min read
174 docs
Balaji
Garry Tan
Shaan Puri
Today’s highest-signal picks include Shaan Puri’s strong recommendation of a Tommy Mello podcast episode (sales/marketing and scaling), Garry Tan pointing back to Paul Graham’s maker-vs-manager schedule framework in a tooling context, and two Balaji reads spanning California wealth-tax policy and pre-1917 Russian intellectual history.

Most compelling recommendation: a sales-and-marketing operator’s scaling story (with a direct link)

Podcast featuring Tommy Mello (YouTube)

  • Content type: Podcast / video (YouTube)
  • Author/creator: Not specified in the post (episode features Tommy Mello)
  • Link/URL: https://www.youtube.com/watch?v=oEXoY3B1-Hw
  • Recommended by: Shaan Puri
  • Key takeaway (as described): Tommy Mello “started off painting garages” and “turned it into a $1B+ biz,” and Shaan calls him an “absolute animal when it comes to sales & marketing.”
  • Why it matters: This is a high-conviction recommendation—Shaan says the podcast is “really really good” and that he “took a lot from this one,” signaling it’s a dense source of practical learning (especially on sales/marketing).

this podcast is really really good


Productivity framework referenced in an AI tooling context

Maker’s vs. manager’s schedule (Paul Graham essay)

  • Content type: Essay / article
  • Author/creator: Paul Graham
  • Link/URL: https://paulgraham.com/makerschedule.html
  • Recommended by: Garry Tan
  • Key takeaway (as described): In the context of “maker’s vs. manager’s schedules,” Tan frames Claude Code as a lever that “lets you squeeze 5 maker’s schedules into your one manager’s schedule.”
  • Why it matters: It’s a pointer to a foundational scheduling framework, shared as the conceptual backdrop for thinking clearly about time fragmentation vs. long, uninterrupted maker blocks—especially when adopting new productivity tooling.

Balaji’s recommended reads (politics + historical analogy)

California wealth tax billionaires proposal (Tax Foundation article)

  • Content type: Article
  • Author/creator: Not specified in the post (Tax Foundation)
  • Link/URL: https://taxfoundation.org/research/all/state/california-wealth-tax-billionaires-proposal/
  • Recommended by: Balaji
  • Key takeaway (as described): Balaji suggests reading it “to get a sense of the seizures underway,” and then “extrapolate that out a few years to realize what’s in store for Silicon Valley.”
  • Why it matters: Offered as a lens for interpreting current policy moves and their potential downstream implications for Silicon Valley, as Balaji frames them.

Russian Cosmism (MIT Press book)

  • Content type: Book
  • Author/creator: Not specified in the post
  • Link/URL: https://mitpress.mit.edu/9780262037433/russian-cosmism/
  • Recommended by: Balaji
  • Key takeaway (as described): He recommends reading about Russia prior to the 1917 Communist Revolution, claiming it had “a thriving stock market” and a “technologist class (the cosmists)” before “their society was destroyed by the Bolsheviks.”
  • Why it matters: Positioned as historical background that supports Balaji’s broader line of comparison about societal/political disruption and what he believes could rhyme with the present.
An essential AI-risk essay, a liquidity-cycle lens on Bitcoin, and Tim Ferriss’s book stack
Jan 27
3 min read
125 docs
Dario Amodei
jack
Tim Ferriss
+3
Today’s strongest signals: Patrick O’Shaughnessy points to Dario Amodei’s AI-risk essay as “essential reading,” Jack Mallers recommends Arthur Hayes’ “Frowny Cloud,” and Tim Ferriss shares a compact stack of books spanning lucid dreaming, nonfiction craft, and relationship communication.

Most compelling recommendation: a clear-eyed AI risk essay (with a direct link)

The Adolescence of Technology

  • Content type: Essay
  • Author/creator: Dario Amodei
  • Link/URL: https://www.darioamodei.com/essay/the-adolescence-of-technology
  • Recommended by: Patrick O’Shaughnessy
  • Key takeaway (as described): An essay on risks posed by powerful AI to national security, economies, and democracy, and “how we can defend against them.”
  • Why it matters: It’s presented as a must-read, high-level framing of societal and geopolitical risk from frontier AI—directly endorsed as “essential reading.”

“Absolutely essential reading”


Markets, liquidity, and Bitcoin as “monetary technology”

Frowny Cloud

  • Content type: Article (Substack)
  • Author/creator: Arthur Hayes
  • Link/URL: Not provided
  • Recommended by: Jack Mallers
  • Key takeaway (as quoted in the recommendation context):
    • Hayes argues that “technology growth stocks rise exponentially… during periods of excess liquidity,” and frames Bitcoin as “monetary technology.”
    • He also claims Bitcoin’s value is tied to “fiat debasement,” and connects Bitcoin’s rise to “an explosion in the supply of dollars post the 2008 global financial crisis.”
  • Why it matters: A compact macro narrative that explicitly links risk appetite/liquidity cycles with tech multiples—and positions Bitcoin inside that same mental model.

Tim Ferriss’s recent “queue-worthy” reads (skill-building, perspective, and relationships)

Of Wolves and Men

  • Content type: Book
  • Author/creator: Barry Lopez
  • Link/URL: Not provided
  • Recommended by: Tim Ferriss
  • Key takeaway (as described): A “beautiful” work about “the history of wolves and man,” diving into wolf biology, mythological significance, and how wolves are viewed by “various indigenous cultures.”
  • Why it matters: Ferriss’s endorsement centers on writing quality and breadth—he says it “redefined what was possible within nonfiction writing.”

Exploring the World of Lucid Dreaming

  • Content type: Book
  • Author/creator: Stephen LaBerge
  • Link/URL: Not provided
  • Recommended by: Tim Ferriss
  • Key takeaway (as described): One of the most “impressive” books Ferriss has found for teaching a skill systematically—specifically, how to induce lucidity and become conscious in dreams; he notes it’s not “mysterious,” and that the ability can be cultivated (within laboratory confines).
  • Why it matters: A rare recommendation framed explicitly around systematic skill acquisition rather than inspiration.

Tribe

  • Content type: Book
  • Author/creator: Sebastian Junger
  • Link/URL: Not provided
  • Recommended by: Tim Ferriss
  • Key takeaway (as described): Ferriss calls it a “great book” and says he recommends everyone read it.
  • Why it matters: A strong, broad endorsement—useful as a short-list candidate if you’re looking for a widely recommended, non-technical read.

The 80/20 Principle

  • Content type: Book
  • Author/creator: Richard Koch
  • Link/URL: Not provided
  • Recommended by: Tim Ferriss
  • Key takeaway (as described): A straightforward “read that” recommendation from Ferriss.
  • Why it matters: A classic prioritization lens—flagged here with zero hedging.

The Comfort Crisis

  • Content type: Book
  • Author/creator: Not specified
  • Link/URL: Not provided
  • Recommended by: Tim Ferriss
  • Key takeaway (as described): Ferriss says it “really delves into this” (context not expanded in the excerpt).
  • Why it matters: Included as a pointer for further reading, but the specific lesson Ferriss drew from it isn’t detailed in the excerpt.

Relationships & communication (practical toolkit)

Fierce Intimacy

  • Content type: Audiobook
  • Author/creator: Not specified (named in the excerpt only as the title)
  • Link/URL: Not provided
  • Recommended by: Tim Ferriss
  • Key takeaway (as described): Ferriss recommends it as an audiobook (he notes it “doesn’t even have a print version”) and highlights that it includes “a toolkit for communicating and intimate relationships.”
  • Why it matters: A concrete “toolkit” framing for relationship communication—recommended in a format designed for immediate consumption (audio).
No updates
Jan 26 88 docs
Garry Tan points YC founders to Bryan Johnson’s “Don’t Die” longevity notes
Jan 25
1 min read
138 docs
Garry Tan
Today’s signal is a single, high-context recommendation: Garry Tan points YC founders to Bryan Johnson’s personal “Don’t Die” notes, framing longevity as a prerequisite for navigating a world shaped by superintelligence.

Most compelling recommendation: Bryan Johnson’s “Don’t Die” personal notes (longevity)

  • Title: Don’t Die (personal notes, as referenced)
  • Content type: Personal notes / longevity guidance (shared with a founder cohort)
  • Author/creator: Bryan Johnson
  • Link/URL: Not provided (Tan references the notes being shared with the new YC batch)
  • Recommended by: Garry Tan (YC President & CEO)
  • Key takeaway (as described): Tan frames longevity as enabling optionality: with “superintelligence around the corner,” we can “choose new games,” and those games “require longevity” .
  • Why it matters: This is a direct, practical recommendation in a high-trust context (materials shared to help a new YC batch), emphasizing longevity as foundational—not as an end in itself, but as a prerequisite for future ambition .

"With superintelligence around the corner, we can choose new games, all of which require longevity"

"Always inspiring @bryan_johnson"