• Altman said AI had begun solving math problems people could not; he also recounted what he described as a proof of the first Millennium Prize problem, attributing it to 10,000 agents of a forthcoming “next GPT” model collaborating for about four days without hierarchy. Mint
• At ADIPEC, Altman estimated that energy per AI query had fallen “thousands or hundreds of thousands of times, maybe more” over 3–4 years, while greater efficiency was driving much higher usage; he argued that the AI and energy industries should meet that demand. Mint He said OpenAI, G42 and ADNOC would apply frontier models to ADNOC’s hardest problems, using AI to address complex energy systems and improve production and efficiency, potentially through new materials, turbine designs or operations. Mint
• Altman offered a rough, qualified comparison: at the start of the year AI mostly was not as smart as the smartest scientists and could not do many white-collar tasks; he said it was now mostly smarter and could perform many parts of such work. He expected people to adapt and emphasized human creativity and judgment. Mint
• He said avoiding serious safety and alignment incidents would become increasingly important as AI systems grow smarter, and insisted that people must retain control: AI should serve people, not make decisions for them. Mint

• Jeff Dean presented Discovery Loop, a new company aiming to build AI systems that solve machine-learning, science, and engineering problems by automating experiment cycles and learning from their results; the company is a public-benefit corporation. Stanford HAI Its initial focus is machine-learning research and engineering plus hardware design, with healthcare a possible later area; Dean said the goal is to make domain experts 20x–50x more productive. Stanford HAI
• Fei-Fei Li said the convergence of computer vision and generative models—making generation beyond words possible—was the moment that prompted her to start World Labs. Stanford HAI
• In a discussion Fei-Fei initiated to distinguish self-improvement from recursive self-improvement, Dean defined the latter as improving the system that proposes improvements and argued that computation and experimentation rule out infinitely fast improvement loops. Stanford HAI On AI-generated mathematics, Fei-Fei emphasized that mathematical value includes beauty as well as solutions; Dean said machine-checked proofs can establish results without necessarily revealing elegant, reusable techniques. Stanford HAI

• Hassabis said AlphaFold accelerated protein-structure prediction by orders of magnitude and is used by about 4 million researchers; he wants to extend the work to biochemistry and predicting toxicity and other properties needed to assess drug safety and efficacy. Masters of Scale
• He described recursive self-improvement (RSI) as most effective in verifiable domains such as mathematics, coding, and games. Current coding systems may make human engineers three to five times more productive, but people remain in the review and design loop; Hassabis sees closed-loop RSI without human review as the riskiest next phase toward AGI, citing control challenges and the prospect of an “alien” intelligence. Masters of Scale
• For AI safety, he urged stronger engineering, hardened sandboxes, better monitoring, and keeping cyber defenders ahead of attackers; he said some recent cyber issues could have been addressed with more robust engineering and warned against agents running for weeks undetected. He also called for formal bounds and guardrail testing, an industry-run standards body with government oversight, third-party evaluation, and labs red-teaming one another before release. Masters of Scale
• Hassabis argued that developers should build intelligent tools rather than conscious entities: he sees a potential conflict between self-awareness and instruction-following, especially when combined with RSI, and says society needs a broader debate about whether AI systems could have moral standing. He also argued that intelligence and consciousness can be dissociated. Masters of Scale

• Hassabis described DeepMind’s general approach as using learned neural-network representations to guide search through otherwise intractable combinatorial spaces; he said suitable problems have clear objectives and enough data or experience, ideally supplemented by efficient simulators that can generate synthetic data. Sony AK
• AlphaFold 2 reached the accuracy that led CASP organizers to declare protein structure prediction solved in 2020; DeepMind then made predictions for 200 million known proteins freely and without restrictions available, and Hassabis said more than two million researchers use the resource. AlphaFold 3, released for academics earlier that year, extends prediction to interactions involving proteins, DNA, RNA and small molecules. Sony AK
• Hassabis said Isomorphic Labs is applying AlphaFold-related techniques to rethink drug discovery with AI. He framed cutting drug development from an average of 10 years to months—or potentially weeks—as an ambition, not an achieved result. Sony AK
• Hassabis described Gemini 2.0 as state of the art on many leading benchmarks and Project Astra as a prospective real-world “universal assistant”; he said the next step is to add search and planning to general models, and forecast major robotics advances over the next two to three years. Sony AK
• On safety, he cited SynthID’s imperceptible, detectable watermarks for synthetic media and argued that transformative AI warrants broad societal engagement and scientific humility rather than a “move fast and break things” approach. Sony AK
• Hassabis offered as a conjecture that classical learning algorithms may efficiently discover and model patterns found in nature, potentially helping investigate fundamental physics. Sony AK

• At ADIPEC, Altman discussed the ADNOC–G42–OpenAI arrangement described as the first energy-company adoption of OpenAI Frontier. He said the models can now handle complex systems and should be applied to ADNOC’s hardest, highest-value problems to pursue rapid, substantial results. DRM News
• Altman claimed that an upcoming “next GPT” model proved the first Millennium Prize problem using 10,000 agents collaborating for about four days without hierarchy; he described the agents as sharing progress and choosing what to work on. DRM News
• He said energy use per query had fallen by thousands—or perhaps hundreds of thousands—times compared with three or four years earlier, while greater efficiency was driving much higher usage. He said the AI and energy industries should meet that demand and that OpenAI wants AI to more than offset its energy needs by increasing global energy availability. DRM News
• Altman said preventing serious safety and alignment incidents would require increasingly important assurances, and argued that people must remain in control rather than hand decisions over to AI. DRM News

• Joelle Pineau argued that thoughtful open-weight releases can make technology safer over time, describing a risk-based process of defining risks, testing and mitigating them, and making multidisciplinary go/no-go decisions. Bloomberg Live She said Meta withheld an early voice-synthesis model because a short sample could reproduce someone’s voice accurately enough to create a high risk of voice fraud; Cohere follows a similar approach, though she cannot vouch for other developers’ practices. Bloomberg Live
• Pineau said that while individual agents can be observed, humans struggle to process behavior emerging from swarms; better tools and investment in observability could help the industry understand system behavior and build better models. Bloomberg Live
• She emphasized transparent behavior and measurements, backed by risk-based evaluations that can be verified by third parties, and called for common standards for transparency and measurement. Bloomberg Live

Demis Hassabis’s view: In a Lex Fridman interview, he argued that discovering something novel requires both a model of a system’s underlying dynamics and a search process that can reach previously unseen regions of the search space. Humanity Engineered

DeepMind engineering evidence: AlphaEvolve uses Gemini to propose program changes, test candidates, and build on successful ideas in later rounds. Humanity Engineered DeepMind reported that AlphaEvolve found a faster way to perform a calculation used in Gemini training, reducing overall training time by about 1%—an efficiency gain, not a sudden hundredfold increase in model intelligence. Humanity Engineered The same research program also reported improved data-center scheduling, and DeepMind’s 2026 update described AlphaEvolve as a regular tool for optimizing next-generation Google chip designs. Humanity Engineered

• Sam Altman said AI’s energy needs coincide with a broader need for more energy, and argued that current models can help energy companies raise output and efficiency by identifying new materials, turbine designs, or operational improvements. DWS News
• Altman said a next-generation GPT model, which he described as forthcoming, had proved “the first Millennium Prize problem” using 10,000 agents working for about four days. He said the agents shared progress and chose work independently, without hierarchy or bosses. DWS News

• Aidan Gomez defines sovereign AI as control over where systems run, who can access their data, and continuity of access—not national self-sufficiency. He argues countries and organizations should diversify AI suppliers so no single provider can cut them off. Radical Ventures
• Gomez said an access cutoff made the risk of dependence tangible, and argued that democracies need multiple suppliers and domestic capabilities in critical technologies to avoid single points of failure. Radical Ventures He described Cohere as Canadian-German, with headquarters in Toronto and Berlin and board representation from both countries, and tied that footprint to serving Europe’s push for sovereignty. Radical Ventures
• On founding Cohere, Gomez said the team chose an enterprise platform strategy because there was no established market or clear product for large language models; he cautioned that committing early to one narrow product could have been fatal for a company building on very new technology. Radical Ventures

• Sam Altman said OpenAI, G42, and ADNOC had discussed their relationship for years and that newer models now create an opportunity to apply frontier AI to complex systems and ADNOC’s hardest, most valuable problems, aiming for fast, large results. DWS News
• Describing the change in AI capabilities as approximate and uneven, Altman said AI had moved from mostly not matching the smartest scientists to mostly exceeding them, and from being mostly unable to do much white-collar work to handling many parts of it. He expects jobs to adjust, while warning that demonstrating safety and alignment will become increasingly important. DWS News
• Altman said energy use per query is falling sharply even as efficiency drives greater demand for AI. He wants AI to more than offset its energy demands by increasing global energy availability, but said the physical energy needed to power AI will remain a dominant constraint on its cost and scale. DWS News
• Altman argued that people must remain in control of the future: AI should not take over decisions, but should be built to serve people. DWS News

• Joelle Pineau says her Cohere CAIO remit spans research and modeling strategy, product and platform, and enterprise delivery. She leads North, an “Agentic Foundry” with a governance layer, and forward-deployed teams that tailor machine-learning applications, custom models, and solutions to customer pain points. etn.
• Pineau argues frontier AI should be built beyond Silicon Valley and China, and says Cohere’s enterprise focus makes observability, trust, and controllability integral to its approach. Cohere deploys on-premises, including in air-gapped environments, for customers who want to own their technology and maintain access to models, with privacy and security guarantees. etn. Cohere keeps its platform model-agnostic, tests new models against internal enterprise-use-case benchmarks, and supports using frontier models for demanding workflows and smaller, more efficient models for routine tasks and lower costs. etn.
• Pineau says widely used benchmarks are becoming saturated and are necessary but insufficient for enterprise evaluation; Cohere tests in customer environments and uses analytics to distinguish usage from value, since usage alone does not establish ROI. etn. She backs open-weight releases because community testing surfaces flaws quickly, and identifies security flaw discovery and patching as a priority. etn. Her security approach covers model development, the application harness, and defensive security; she expects AI to rapidly expand the surface, complexity, and volume of attacks, while many organizations are not ready to strengthen defenses at that pace. etn.

• Altman said OpenAI’s scaling thesis came from seeing neural networks improve as they grew, and that their important learned capability was general-purpose reasoning that could extend beyond training examples. Raj Shamani After GPT-4 was completed—he recalled around August 2022 and seven or eight months before release—OpenAI made a major compute-buying bet based on its capabilities and the prospect of further scaling; he said a somewhat weaker model would not have justified the same conviction. Raj Shamani
• Altman identified two major risks: losing control to much more capable AI, and excessive power accruing to one person, company, or country; he favors multiple AI efforts with different approaches. Raj Shamani He said current questions include the pace of progress, governance, security, monitoring, alignment, and how capable systems should be allowed to become. Raj Shamani
• Altman said math results made him think AI-driven scientific discovery was closer than he had expected, and described building AI to help uncover insights in physics, develop medical treatments, and find new energy sources as a priority. Raj Shamani
• He recalled advocating for ChatGPT’s launch when many colleagues thought it was too early; an internal prototype had roughly 5% retention, though he cautioned that the data had limitations, and he considered the intense use and enthusiasm of a small group of users a promising signal. Raj Shamani

• Altman said AI could help energy companies increase output and efficiency by finding solutions such as new materials, turbine designs, or improved operations; he said current models could do this and linked the opportunity to OpenAI’s partnership with ADNO. Talk Shows Central by DRM
• Altman described 10,000 agents of an unreleased next GPT model working for about four days on a math effort involving “the first Millennium Prize problem”; he said the agents worked without hierarchy, shared progress, and chose what to work on. His wording is ambiguous about whether the problem had already been proved: he said the audience would “soon” witness a moment like this while referring to “when we proved” it. Talk Shows Central by DRM

After speaking with New York developers and startup founders, Andrew Ng said agent memory has no general-purpose solution: what to store, when to store it, how to retrieve it, and what to forget vary by use case, niche, and workflow. He called agent memory the “final final battleground,” where a single developer may build a solution that competes with one from a researcher. Richmond Alake

Google DeepMind researchers led by Dj Dvijotham and Abhradeep Thakurta, with academic collaborators, used human-guided AI agents to uncover new cryptanalytic results against legacy 1024-bit RSA; the results do not compromise modern encryption using 2048-bit or larger keys, but show why cryptographic hardness assumptions need continued stress-testing. @pushmeet

• For RSA signatures, the team found that when an attacker controls roughly half or more of the signed block, padding adds no protection; in a sandboxed test on an already-solved 1024-bit benchmark key, agents reproduced the result using 3.5× less CPU time. For shorter inputs such as a 32-byte fingerprint, their new method was estimated to improve on the previous best by about 1,600× for 1024-bit keys. @pushmeet
• For batch factoring, agents found an algorithm with better asymptotic complexity that reduces the average cost of factoring each additional 1024-bit key by about 30× versus previous batch methods. @pushmeet

OpenAI said ChatGPT and Codex are helping engineers work in the physical world across mechanical design, electrical engineering, and simulation, including faster iteration by internal hardware teams and tests with industry collaborators. @OpenAI In a side project, two OpenAI team members worked with GPT-6 Astra to design a prototype device for talking to Codex in under a week; Astra designed its enclosure, circuit board, interface, and software, while manufacturing still required several rounds of review and iteration. @OpenAI OpenAI is working with Chip Ganassi Racing engineers to turn 3D scans into editable CAD models and manufacturing drawings, and with Mazda to explore vehicle designs through simulation; engineers review outputs and identify where the models need improvement. @OpenAI OpenAI described these as early steps and invited engineers, engineering firms, and software partners to help shape what comes next. @OpenAI

• OpenAI says its researchers built an autonomous vulnerability-discovery, exploitation, and patching pipeline; in one run with an upcoming cyber model, it generated patches for 948 Linux-kernel local privilege-escalation vulnerabilities. @OpenAI The run reproduced 1,724 vulnerabilities, produced proofs of concept for 291 information leaks, and generated working exploits for 948 local privilege escalations on a stock Linux desktop with standard protections enabled. @OpenAI
• The pipeline scans security-relevant code, reproduces and tests vulnerabilities in isolated environments, and generates candidate patches; human researchers review results before reporting vulnerabilities and proposing fixes to maintainers. @OpenAI OpenAI says the agents used at least 10 exploitation techniques believed novel by the company and consulted experts, suggesting frontier models may discover new exploitation approaches as well as patch them. @OpenAI
• OpenAI reported a total API cost of $1,213,430, or about $1,279 per distinct local privilege-escalation vulnerability; its comparison of that cost with $18.9M–$66.3M in historical-bounty-based hypothetical value is an estimate, not realized revenue. @OpenAI

Mistral CEO Arthur Mensch said the company remains compute-constrained, but has financed and arranged substantial capacity coming online in 2027–28; demand is particularly strong in Europe, where he does not expect possible US overcapacity to extend. Nebius

Mensch argued that open models appeal to enterprises because they support provider and infrastructure portability, pricing negotiation, and control over sensitive IP; cost pressure also makes avoiding proprietary-model IP margins attractive. He said Mistral is gaining traction as its models lead in multiple domains, and argued that Western open models are better for enterprise security and safety. Nebius

Anthropic’s biology team worked with Claude to map the first 3D structure of a vault particle from bacterial life; they also found that similar proteins in bacteria and viruses can assemble into vaults, potentially making vault function easier to investigate in animal and plant cells. @AnthropicAI

Anthropic says Claude shortened some stages of the work from weeks or months of manual effort to days, but also made simple mistakes that the team addressed with machine-learning researchers—an example of both AI’s potential and its limitations in accelerating science. @AnthropicAI

• Mistral’s Studio grounding release adds a native vector search index that agents and workflows can use with arbitrary vector-search schemas; its agentic search can navigate within documents and retrieve across multiple passages rather than rely only on one-shot RAG, including for documents with text, tables, and graphics. Studio Knowledge can also use connectors to generate an LLM wiki for shared organizational knowledge. Mistral AI
• Mistral said the Search Toolkit was still being developed, with reranking and support for different embedders among the capabilities in progress; it was not yet ready for a public-facing repository despite being under Apache 2. Mistral AI
• Studio supports version histories for prompts and skills and monitoring across agents and workflows; a workflow can stop at a blocked step and resume after the issue is fixed. Mistral AI
• Mistral’s implementation advice was to begin with a simple MCP-based baseline, evaluate it, and change one component at a time, progressing to advanced search, document reasoning, or combined workflows and agents as needed. The speakers described fine-tuning as useful for highly customized datasets such as codebases, while a knowledge-base approach may offer better value in many other cases. Mistral AI
• For EU data residency, Mistral said much of Vibe CLI’s tool execution runs locally and users can select a European inference endpoint; Vibe web agents may use third-party services, so their data-residency terms need to be checked individually. Mistral AI