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Top pick: "The Amazon Trap" by @mvernal, recommended by Sarah Guo and Scott Belsky
What it argues: Vernal's essay is billed as "Why Amazon is blocking Instinct & Muse, and one potential path forward" . He says horizontal personal agents will win because they have "the totality of their context," including email, calendar and files. That leaves Amazon with two choices. It can give up a core strategic position and up to $80B a year in ad revenue, or it can antagonize its customers . His proposal is a "Prime+" tier at roughly $299 a year, with agentic purchasing available only to its members . Disclosure: his firm was Instinct's initial investor, sits on its board and seeded the team now working on Muse .
Why they shared it: Guo called it "some strategic wisdom from our partner" on "the choice of whether to resist the future or rapidly adapt" . Belsky quoted the line "Companies often anchor to their priors." He added that "you can't fight customer preferences for horizontal agents, you must innovate to meet them," and said he'd like to hear what Andy Jassy thinks .
Bill Gurley: "Machines of Loving Grace" by Dario Amodei
This follows Gurley's push for the NYT piece on Anthropic, covered in the last brief. A reply argued that Anthropic's approach differs from other labs' and that, under it, "the machine will inevitably control humans" . Gurley pointed to Amodei's essay and said the view is "directly stated" there. He added that the company makes job candidates read the essay and "even hands out to customers" . He doesn't say whether he agrees with it. His point is that the essay is the place to understand how Anthropic thinks.
Paul Graham: Christian Szegedy's personal essay on AI and mathematics
Szegedy says he wrote the essay after reading recent essays by Terry Tao, Kevin Buzzard and Timothy Gowers . Graham shared it with this quote: "The skeptics who say AI can't conjecture, can't theorize, and can't explain are describing last spring's models. Within months, they will be describing nobody" .
Amjad Masad: a16z podcast with OpenRouter's Alex Atallah
Masad is a guest on this episode and co-founded Replit, so it is partly self-promotion. He said the conversation goes "really deep and somewhat technical" and called Atallah "brilliant" . It is Atallah's first podcast since Stripe acquired OpenRouter . Topics include:
- how the Stripe deal came about
- why "payments and inference are going to blend together"
- why enterprises are spreading their usage across labs and open-weight models
The two disagree on personal agents. Masad runs one agent across his whole company. Atallah argues that "10 specialized chiefs of staff beats one superagent" . YouTube.
Shorter mentions
- The Best of Om Malik by Elijah Potter (@theleastsirius), recommended by Matt Mullenweg. Potter put it together after discovering Malik's archives. Mullenweg said it makes him "very happy that a new generation is revisiting Om's writing." He added that Malik's work "really shaped a lot of my thinking" . This follows his praise last week for another tribute to Malik.
- Social Capital's post on the economics of aging, shared by Chamath Palihapitiya. Social Capital is Chamath's own firm. He framed the post as "The case for giving everyone GLPs…" . The post estimates that slowing aging by one year would add about $400B a year to U.S. GDP, and that slowing it by five years would add $2T. It sets this against Social Security and Medicare spending of roughly $2.6T in 2024 .
The interviewee credited How to Change Your Mind by Michael Pollen, which he found through the New York Times’ 2017 10 best books list, with “literally” changing his mind. He said it moved him from having no prior interest or knowledge of psychedelics to believing the medicines could be useful, citing academic results on PTSD, depression, and anxiety.
Jason Lemkin shared his new SaaStr article, “We Vibe Coded Our Own Calendly. Our AI Agent Pushed Us To Do It, and It Was Right”, presenting the build as an instance where the AI agent was right to push the team to act . The post says AI VP 10K built it on Replit in 20 minutes; it generates a live prospectus for each sponsor prospect and routes them to the right rep .
Sarah Guo recommended partner @mvernal’s article “The Amazon Trap” as “some strategic wisdom” on whether companies should resist the future or rapidly adapt . The essay argues horizontal personal agents will work and suggests Amazon adapt by offering agentic purchasing through a premium Prime+ tier .
Fred Wilson praised a video conversation between himself and Nikhil (@uninsightful), arranged by Matt Cynamon and recorded at the USV CEO Summit after Labor Day. Wilson described it as Nikhil interviewing him alongside a discussion of the VC business in 2026, and said it had “Lots of gems.” He linked Cynamon’s post with the conversation.
Paul Graham highlighted Chr Szegedy’s post with the argument that skeptics of AI’s ability to conjecture, theorize, and explain are judging last spring’s models, and that the evidence for progress is already visible. Szegedy’s post links to his personal perspective document, which he says was prompted by reading essays by Terry Tao, Kevin Buzzard, and Gowers: Google Doc.
Responding to a claim about Anthropic’s approach to keeping humans in control, Bill Gurley pointed to Dario Amodei’s essay “Machines of Loving Grace” as stating the view directly; he added that Anthropic makes employment candidates read it and gives it to customers. Essay
Marc Benioff gave an appreciative shout-out to @javif4_’s post, which presents “ANY DAY NOW (The Robots Are Coming)” as the creator’s first song; Benioff wrote, “So many videos, So little time! ❤️” . The creator says the piece used Suno and Midjourney, 116 clips made with Kling and Wan, and Claude for every word and graphic on the beat .
Chamath Palihapitiya pointed followers to Social Capital’s X post, framing it as “The case for giving everyone GLPs…” The post argues that slowing aging by one year could add about $400B annually to U.S. GDP, and by five years $2T; it presents even a small shift in biological aging as an economic opportunity amid rising Social Security and Medicare spending.
Scott Belsky shared and endorsed @mvernal’s article “The Amazon Trap,” introduced as “Why Amazon is blocking Instinct & Muse, and one potential path forward.” He highlighted the article’s observation that companies anchor to their priors and added that businesses must innovate to meet customer preferences for horizontal agents, not fight them.
Jason Lemkin (@jasonlk) pointed readers to a SaaStr teardown of how SaaStr AI runs inbound, renewals, and outbound with its latest agents, introducing it only as “More here” without stating a specific reason for recommending it. The surrounding post describes SaaStr AI’s 10K learning about prospects, building customized decks, and booking meetings before they leave the SaaStr AI Annual website.
Scott Belsky shared and praised N Biers’ X post, calling its vision of “talent dense, aligned, flat, and empowered teams” “the magic” (post). Biers’ post describes ElonCo’s ability to pivot to urgent problems and let employees raise alarms, act, or rally others, while noting that this is difficult to achieve in larger companies.
Elon Musk shared Sawyer Merritt’s post featuring Jason Oppenheim’s Tesla FSD testimonial video, writing that FSD “feels like magic.” Oppenheim describes FSD as life-changing and safe, and says he is buying Teslas with FSD for 10 employees.
Elon Musk affirmed Rothmus’s post with “Exactly,” endorsing its argument that humanoid robots can raise productive capacity. The post identifies energy as the binding input and says multiplanetary expansion adds land, minerals, and generation.
Amjad Masad recommended an a16z-posted podcast conversation featuring OpenRouter co-founder Alex Atallah, Masad, and a16z’s Erik Torenberg, calling it “really deep and somewhat technical” and Atallah “brilliant.” The conversation covers OpenRouter’s Stripe acquisition, mixing AI models, enterprise independence, and general versus specialized agents. Watch on YouTube.
Brian Armstrong urged followers to tune in to Coinbase’s upcoming in-person crypto trading contest, where favorite traders would compete on Coinbase Advanced for a $150,000 prize. Coinbase said the Singapore event would be streamed live on X on October 8.
Matt Mullenweg endorses “The Best of Om Malik”, linked from Elijah Potter (@theleastsirius) after Potter discovered Om’s archives; Mullenweg says Om’s writing shaped much of his thinking and that he is happy a new generation is revisiting it.
The Amazon Trap

I love Amazon – both the product and the company. It’s the reason I find Amazon’s reaction to Instinct and Muse so jarring:
https://x.com/i/web/status/2104988337660420186 (opens in new tab)
I’m not mad at Amazon – I get it.
Over the past 20 years, Amazon did the impossible – they wrested a search vertical out of Google’s hands.
In the early days of the Internet, it was unclear if there would be a single search engine to rule them all or a set of vertical search engines. Consumers’ revealed preference was that they wanted a single place to ask all questions. Vertical search experiences (local, travel) slowly collapsed into the core Google search product.
There was one exception – shopping (and Amazon).
Amazon built an incredible shopping experience – the Everything Store – and then trained users that it was faster to start their shopping experience on Amazon, not Google.
This was not an accident – it was relentless execution. Amazon has an incredibly sophisticated SEO strategy. They don’t let Google index their whole product catalog. Many SEO links lead to a category page at Amazon designed to capture your search intent and train you to start your search on Amazon. Amazon has spent 15 years moving your search behavior from Google to their product. The $80B advertising business is the reward (and that $80B comes at Google’s direct loss).
This is why I empathize with Amazon’s current predicament. On the one hand – they have spent 20 years fighting to make Amazon the starting point for online commerce. They have done that – in part – by building a beloved, customer-delighting product rooted in ever-rising customer expectations.
Horizontal consumer assistants are going to work
I have been using Instinct for a while (disclosure, we are the initial investors and on the board). I have also been using Muse since launch and know many of the folks on the team (we were also seed investors in the Dreamer team, which now works on Muse!). They are both great products.
They’re both going to work.
Personal agents are just such a better experience. I had to book a hotel in NYC yesterday. With Instinct, I can just say “Can you book me a room at [the hotel] on the 21st?” It has my credit card and flight info. It knows what rooms I’ve booked before. It has my loyalty number. It can just book the room and add it to my calendar in just the way I like it. It’s not going to make a mistake with the dates. It is so much better than a dozen, slow-loading, form-heavy hotel web pages.
Given both my respect for Amazon and my belief that Instinct and Muse will work, I have been spending the past couple of days trying to think through the game theory of how this market will play out. What would I do if I were Andy Jassy?
Companies often anchor to their priors.
In this case, I suspect Amazon will default to the Amazon / Google playbook of the past two decades, i.e., make Amazon the “personal assistant for shopping.”
Amazon seems to be trying this. Over the past month, an “Alexa for Shopping” tab has appeared (and tends to randomly expand) on the Amazon home page:

On paper, this is a plausible strategy.
The problem is – I don’t think it’s going to work.
The magic of horizontal personal agents is the totality of their context – your email, calendar, files, messages, etc. In the same way that Google was the home page for the Internet, products like Instinct will be the starting point for anything you want to do. I don’t want to go to one agent to order food, another to book a car, another to book a trip, and another to buy baseball socks for my kids. I just want to be able to text a single agent that can figure it out and gets smarter with each interaction.
This puts Amazon in a Catch 22 – give consumers what they want and give up a core pillar of their strategic positioning (not to mention $80B/year of ad revenue), or stall and antagonize their consumers in the hope that horizontal agents don’t work.
The problem is – they’re going to work. And the optimal strategy for Amazon’s competitors is to go all-in on supporting these agents. If the market is shifting and Amazon refuses to participate, this creates a huge opportunity for Walmart, Shopify and others to steal market share as consumer demand evolves.
What should Amazon do?
Amazon should launch a new subscription tier above Amazon Prime. Call it Prime+.
Amazon Prime is $139/year in the US today and I think >65%(!) of US households are subscribers.
Set the Prime+ pricing at something like $299/year or $30/month. Make agentic purchasing exclusive to this tier. This solves multiple problems at once:
It gives Amazon a way of saying yes to its most loyal customers
It provides replacement revenue for any potential lost advertising revenue
It lets Amazon dip its toes into agentic use cases without betting the farm
Amazon doesn’t even need to market this aggressively to customers – leave that job to tools like Muse and Instinct: “To order from Amazon, you need to upgrade to Amazon Prime+ for $40/month or $399/year – do you want me to upgrade your plan?”
I think Amazon would be surprised by the uptake.
There is already some precedent for this. What is YouTube Premium? It is a way for consumers to pay for the convenience of an ad-free YouTube experience. Amazon Prime+ is the same thing – a way for consumers to pay for the convenience of an ad-free, agentic Amazon experience.
YouTube Premium customers are some of YouTube’s most avid, loyal customers. The same will be true of Amazon Prime+. Every consumer product developer knows decreasing friction increases conversion – I suspect that enabling agentic use will meaningfully increase Prime+ ARPU, too.
Uber, DoorDash and Instacart each have their own loyalty programs with similar dynamics (Uber One – $96/year, DashPass – $96/year, Instacart+ – $99/year). I don’t know if they share Amazon’s trepidation about enabling agentic use. But if they do, this offers a similar path forward.
Is this the market equilibrium?
I don’t know.
If I were a competitor, I would optimize for agentic use to try to take market share. Markets don’t reconfigure often.
But here’s the thing – I don’t want to leave Amazon. Would I prefer to just have them enable agentic shopping for free? Of course. But if given the choice, I would rather just pay more to have the Amazon experience within experiences like Instinct and Muse than explore other shopping tools.
Amazon Prime led to the most engaged customers buying more, more often. I think there’s a good chance that Prime+ will do the same. Maybe the marginal user will give Walmart a try, but I suspect the incrementality of Prime+ might outweigh the loss from marginal switchers. It seems worth a try.
Divine Discontent
This is the crux of the innovator’s dilemma – you’re damned if you do, damned if you don’t. I understand why marketplaces will want to stick their head in the sand. Apple has been fighting tooth-and-nail to keep the App Store tax for almost twenty years.
But I think there is another way for now. Introduce a new, premium tier. Enable agentic access there first. Keep your most active, tech-forward customers happy while you let the broader market shake out. I am confident that both (a) horizontal, personal agents are the way forward and (b) beloved consumer services like Amazon will find a way.
Consumer expectations are not static – they only ever go up. Those that meet these ever-increasing expectations are the ones that will ultimately win.
Why Amazon is blocking Instinct & Muse, and one potential path forward https://x.com/i/article/2106391810331574272 (opens in new tab)
Sarah Guo recommended partner @mvernal’s article “The Amazon Trap” as “some strategic wisdom” on whether companies should resist the future or rapidly adapt . The essay argues horizontal personal agents will work and suggests Amazon adapt by offering agentic purchasing through a premium Prime+ tier .
Scott Belsky shared and endorsed @mvernal’s article “The Amazon Trap,” introduced as “Why Amazon is blocking Instinct & Muse, and one potential path forward.” He highlighted the article’s observation that companies anchor to their priors and added that businesses must innovate to meet customer preferences for horizontal agents, not fight them.